22/10/2018 – Reducing further damage after stroke

After a stroke, the inflammation that clears up the damage can remain active for too long. That results in extra damage. The NAVISTROKE project investigates whether nanoparticles with cannabis-like substances can dampen or prevent harmful effects.

In the Netherlands, about five people will have a stroke in the next hour. The next hour, five others and that goes on continuously, day in and day out. We count 125 strokes per day, about 46,000 per year. 9,000 of all people with stroke die. Many of the 37,000 survivors suffer from severe cognitive impairments, movement disorders or other disabilities after the recovery.

The objective is not only to reduce the number of strokes as much as possible, but also to promote the recovery therapeutically. By encouraging people to eat healthy and exercise sufficiently. By reducing the risk with medication where necessary. But even afterwards – if the stroke has already happened – improvement may still be possible. This is the aim of NAVISTROKE (Nanomedicine to Visualize and Treat Inflammation after Stroke). Read the complete article here (in Dutch).

24/05/2017 – Cannabidiol slashes seizures in kids with rare epilepsy, study finds

Cannabidiol, which is found in cannabis plants, reduced the number of convulsive seizures in children with a severe and often fatal epilepsy disorder, according to research published Wednesday in the New England Journal of Medicine. Among children taking cannabidiol, the decrease in the frequency of convulsive seizures — which involve a loss of consciousness, stiffened muscles and jerking movements — was 23 percentage points greater than the decrease in seizures among children taking a placebo. Read the complete article here.

03/05/2017 – Crowd funded High On Nano reaches 1st crucial milestone

On May 2nd 2017,  the High On Nano project reached an important milestone, as a first set of scientific results were published in the high-impact journal ACS Nano. The study was partially funded by Sensi Pharma BV, a company that was established to solidify High on Nano’s success in 2014, and is aimed at developing and applying natural cannabinoids for medical purposes. Using natural molecular building blocks, an international research team, spearheaded by investigators from the Academic Medical Center of the University of Amsterdam, shows that hyaluronan-based nanoparticles (HA-NPs) can be employed to molecularly image atherosclerosis-associated inflammation as well as to effectively ameliorate atherosclerosis. Atherosclerosis is the underlying cause of cardiovascular disease, including heart attack and stroke, and represents the highest expenditure in the world health care. Read the complete press release here.